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Help you modulate immune system

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Help you modulate immune system

About Immune

Why A Healthy Microbiome Matters?
Beneficial gut microorganisms activate immune cells to boost immunity.
If the intestinal microbial balance is broken, the risk of the development
of metabolic diseases such as diabetes and enteritis is higher.
“The gut microbiome and microbiome-associated metabolites
translocate from the intestinal lumen to various organs (e.g., liver, brain or lung)
through the circulatory system, and subsequently induce
tissue-specific local immune responses.“
*Data Resource : Zheng, D., Liwinski, T. & Elinav, E. Interaction
between microbiota and immunity in health and disease.
Cell Res 30, 492–506 (2020).


Two-way Immune Modulation based on Bifidobacterium
  • Activation
    Bifidobacterium-derived signals modulate the activation of DC
    (Dendritic Cell) in a steady state, which in turn supports improved
    effector function of tumor-specific CD8+ T cells.
  • Cell Surface β-glutan/galactan (CSGG) polysaccharides produced
    by Bifidobacterium as the key effector component enable
    the induction of Treg cells via a DC (Dendritic Cell)-dependent
    mechanism with the capacity to ameliorate intestinal
Bifidobacterium & Immune Cells

*Data Resource
1. Science Immunology 19 Oct 2018: Vol.3, Issue 28, Cell surface polysaccharide of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cell.
2. Science 2015 November 27; 350(6264): Commensal Bifidobacterium promotes immunity and facilitates anti-PD-L1 efficacy.

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